Publikationen

2020

• Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction.
  Gebert N, Cheng CW, Kirkpatrick JM, Di Fraia D, Yun J, Schädel P, Pace S, Garside GB, Werz O, Rudolph KL, Jasper H, Yilmaz ÖH, Ori A
  Cell Rep 2020, 31(4), 107565
  
• Local and transient inhibition of p21 expression ameliorates age-related delayed wound healing.
  Jiang D, de Vries JC, Muschhammer J, Schatz S, Ye H, Hein T, Fidan M, Romanov VS, Rinkevich Y, Scharffetter-Kochanek K
  Wound Repair Regen 2020, 28(1), 49-60
  
• Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor.
  Njeru* SN, Kraus* J, Meena* JK, Lechel A, Katz SF, Kumar M, Knippschild U, Azoitei A, Wezel F, Bolenz C, Leithäuser F, Gollowitzer A, Omrani O, Hoischen C, Koeberle A, Kestler** HA, Günes** C, Rudolph** KL
  Oncogene 2020, 39(7), 1445-65 * equal contribution, ** co-corresponding authors
  
• Elevated Hedgehog activity contributes to attenuated DNA damage responses in aged hematopoietic cells.
  Scheffold A, Baig AH, Chen Z, von Löhneysen SE, Becker F, Morita Y, Avila AI, Groth M, Lechel A, Schmid F, Kraus JM, Kestler HA, Stilgenbauer S, Philipp M, Burkhalter MD
  Leukemia 2020, 34(4), 1125-34
  
• The role of Igf2bp2 in hematopoietic stem cell aging
  Suo M
  Dissertation 2020, Jena, Germany
  
• Dietary restriction increases protective gut bacteria to rescue lethal methotrexate-induced intestinal toxicity.
  Tang D, Zeng T, Wang Y, Cui H, Wu J, Zou B, Tao Z, Zhang L, Garside GB, Tao S
  Gut Microbes 2020, 1(1714401), 1-21
  
• High Canonical Wnt/β-Catenin Activity Sensitizes Murine Hematopoietic Stem and Progenitor Cells to DNA Damage.
  Wang Y, Cui H, Tao S, Zeng T, Wu J, Tao Z, Zhang L, Zou B, Chen Z, Garside GB, Tang D
  Stem Cell Rev Rep 2020, 16(1), 212-21
  

2019

• Adaptive immunodeficiency accelerates the development of intestinal atrophy in telomere dysfunctional mice during ageing
  Bajwa S
  Dissertation 2019, Jena, Germany
  
• Igfbp7 knock-down perturbs hemotopoiesis and causes an MPN-like phenotype in aging mice
  Calmes PG
  Dissertation 2019, Jena, Germany
  
• Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.
  Chen Z, Amro EM, Becker F, Hölzer M, Rasa SMM, Njeru SN, Han B, Di Sanzo S, Chen Y, Tang D, Tao S, Haenold R, Groth M, Romanov VS, Kirkpatrick JM, Kraus JM, Kestler HA, Marz M, Ori A, Neri F, Morita** Y, Rudolph** KL
  J Exp Med 2019, 216(1), 152-75 ** co-corresponding authors