Rudolph Research Group

Publications

2020

  • Local and transient inhibition of p21 expression ameliorates age-related delayed wound healing.
    Jiang D, de Vries JC, Muschhammer J, Schatz S, Ye H, Hein T, Fidan M, Romanov VS, Rinkevich Y, Scharffetter-Kochanek K
    Wound Repair Regen 2020, 28(1), 49-60
  • Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor.
    Njeru* SN, Kraus* J, Meena* JK, Lechel A, Katz SF, Kumar M, Knippschild U, Azoitei A, Wezel F, Bolenz C, Leithäuser F, Gollowitzer A, Omrani O, Hoischen C, Koeberle A, Kestler** HA, Günes** C, Rudolph** KL
    Oncogene 2020 (epub ahead of print) * equal contribution, ** co-corresponding authors
  • Elevated Hedgehog activity contributes to attenuated DNA damage responses in aged hematopoietic cells.
    Scheffold A, Baig AH, Chen Z, von Löhneysen SE, Becker F, Morita Y, Avila AI, Groth M, Lechel A, Schmid F, Kraus JM, Kestler HA, Stilgenbauer S, Philipp M, Burkhalter MD
    Leukemia 2020 (epub ahead of print)
  • High Canonical Wnt/β-Catenin Activity Sensitizes Murine Hematopoietic Stem and Progenitor Cells to DNA Damage.
    Wang Y, Cui H, Tao S, Zeng T, Wu J, Tao Z, Zhang L, Zou B, Chen Z, Garside GB, Tang D
    Stem Cell Rev Rep 2020 (epub ahead of print)

2019

  • Adaptive immunodeficiency accelerates the development of intestinal atrophy in telomere dysfunctional mice during ageing
    Bajwa S
    Dissertation 2019, Jena, Germany
  • Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.
    Chen Z, Amro EM, Becker F, Hölzer M, Rasa SMM, Njeru SN, Han B, Di Sanzo S, Chen Y, Tang D, Tao S, Haenold R, Groth M, Romanov VS, Kirkpatrick JM, Kraus JM, Kestler HA, Marz M, Ori A, Neri F, Morita** Y, Rudolph** KL
    J Exp Med 2019, 216(1), 152-75 ** co-corresponding authors
  • Wnt Signaling Mediates the Aging-Induced Differentiation Impairment of Intestinal Stem Cells.
    Cui H, Tang D, Garside GB, Zeng T, Wang Y, Tao Z, Zhang L, Tao S
    Stem Cell Rev Rep 2019, 15(3), 448-55
  • Tnfaip2 induces differentiation of pluripotent stem cells and inhibits induction of pluripotency
    Deb S
    Dissertation 2019, Jena, Germany
  • TRiC activates the unfolded protein response and protects starved stem cells by modulating energy and lipid metabolism during planarian regeneration
    Gutiérrez-Gutiérrez* Ó, Felix* DA, Salvetti A, Thems A, Pietsch S, Koeberle A, Rudolph KL, González-Estévez C
    bioRxiv 2019, https://doi.org/10.1101/732875 * equal contribution
  • Reverse genetic screening identifies essential ribosomal protein genes in hematopoietic stem cells that are dysregulated during aging
    Han B
    Dissertation 2019, Jena, Germany