Herrlich Research Group

Publications

2020

  • A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.
    Köhnlein* K, Urban* N, Guerrero-Gómez D, Steinbrenner H, Urbánek P, Priebs J, Koch P, Kaether C, Miranda-Vizuete A, Klotz LO
    Redox Biol 2020, 28, 101323 * equal contribution
  • CD44 (Cluster of differentiation 44) promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin.
    Ma* J, Klemm* J, Gerardo-Ramírez M, Frappart L, Castven D, Becker D, Zoch A, Parent R, Bartosch B, Minnich K, Giovannini M, Danckwardt S, Hartmann N, Morrison H, Herrlich** P, Marquardt** JU, Hartmann** M
    Int J Cancer 2020 (epub ahead of print) * equal contribution, ** co-senior authors

2019

  • CD44 deletion suppresses atypia in the precancerous mouse testis.
    Li* H, Shukla* S, Frappart L, Herrlich** P, Ploubidou** A
    Mol Carcinog 2019, 58(5), 621-6 * equal contribution, ** co-corresponding authors
  • Novel function of TRIP6, in brain ciliogenesis
    Shukla S, Urbanek P, Frappart L, Hänold R, Nagel S, Monajembashi S, Grigaravicius P, Min WK, Tapias A, Kassel O, Heuer H, Wang ZQ, Ploubidou A, Herrlich P
    bioRxiv 2019, https://doi.org/10.1101/777052

2018

  • Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling.
    Dhar D, Antonucci L, Nakagawa H, Kim JY, Glitzner E, Caruso S, Shalapour S, Yang L, Valasek MA, Lee S, Minnich K, Seki E, Tuckermann J, Sibilia M, Zucman-Rossi J, Karin M
    Cancer Cell 2018, 33(6), 1061-1077.e6
  • Gamma secretase dependent release of the CD44 cytoplasmic tail upregulates IFI16 in cd44-/- tumor cells, MEFs and macrophages.
    Schultz* K, Grieger (Lindner)* C, Li Y, Urbánek P, Ruschel A, Minnich K, Bruder D, Gereke M, Sechi A, Herrlich P
    PLoS One 2018, 13(12), e0207358 * equal contribution

2017

  • ADAM Metalloprotease-Released Cancer Biomarkers.
    Herrlich P, Herrlich A
    Trends Cancer 2017, 3(7), 482-90
  • Spindle Misorientation of Cerebral and Cerebellar Progenitors Is a Mechanistic Cause of Megalencephaly.
    Li H, Kroll T, Moll J, Frappart L, Herrlich P, Heuer H, Ploubidou A
    Stem Cell Reports 2017, 9(4), 1071-80

2016

  • Impaired Planar Germ Cell Division in the Testis, Caused by Dissociation of RHAMM from the Spindle, Results in Hypofertility and Seminoma.
    Li H, Frappart* L, Moll* J, Winkler* A, Kroll T, Hamann J, Kufferath I, Groth M, Taudien S, Schütte M, Yaspo ML, Heuer H, Lange BMH, Platzer M, Zatloukal K, Herrlich P, Ploubidou A
    Cancer Res 2016, 76(21), 6382-95 * equal contribution
  • Growth factor and co-receptor release by structural regulation of substrate metalloprotease accessibility.
    Parra* LM, Hartmann* M, Schubach S, Ma J, Herrlich** P, Herrlich** A
    Sci Rep 2016, 6, 37464 * equal contribution, ** co-senior authors

Best Paper

The JBC paper on Ectodomain Cleavage has been selected as one of the best JBC papers of the year.