von Eyss Research Group

Selected Publications

  • Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation.
    Jaenicke* LA, von Eyss* B, Carstensen A, Wolf E, Xu W, Greifenberg AK, Geyer M, Eilers M, Popov N
    Mol Cell 2016, 61(1), 54-67 * equal contribution
  • Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells.
    Wiese* KE, Haikala* HM, von Eyss* B, Wolf E, Esnault C, Rosenwald A, Treisman R, Klefström J, Eilers M
    EMBO J 2015, 34(11), 1554-71 * equal contribution
  • A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer.
    von Eyss B, Jaenicke LA, Kortlever RM, Royla N, Wiese KE, Letschert S, McDuffus LA, Sauer M, Rosenwald A, Evan GI, Kempa S, Eilers M
    Cancer Cell 2015, 28(6), 743-57
  • The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.
    von Eyss B, Maaskola J, Memczak S, Möllmann K, Schuetz A, Loddenkemper C, Tanh MD, Otto A, Muegge K, Heinemann U, Rajewsky N, Ziebold U
    EMBO J 2012, 31(4), 972-85
  • The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis.
    Osterloh* L, von Eyss* B, Schmit F, Rein L, Hübner D, Samans B, Hauser S, Gaubatz S
    EMBO J 2007, 26(1), 144-57 * equal contribution

Publications at FLI

2017

  • OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
    Jung LA, Gebhardt A, Koelmel W, Ade CP, Walz S, Kuper J, von Eyss B, Letschert S, Redel C, d'Artista L, Biankin A, Zender L, Sauer M, Wolf E, Evan G, Kisker C, Eilers M
    Oncogene 2017 (epub ahead of print) published during change of institution

2016

  • TEAD activity is restrained by MYC and stratifies human breast cancer subtypes.
    Elster D, Jaenicke LA, Eilers M, von Eyss B
    Cell Cycle 2016, 15(19), 2551-6
  • Different promoter affinities account for specificity in MYC-dependent gene regulation.
    Lorenzin F, Benary U, Baluapuri A, Walz S, Jung LA, von Eyss B, Kisker C, Wolf J, Eilers M, Wolf E
    Elife 2016, 5 doi: 10.7554/eLife.15161